Plant Transcription Factor Database
Previous version: v3.0
Fragaria x ananassa
FAR1 Family
Species TF ID Description
FANhyb_icon00000086_a.1.g00001.1FAR1 family protein
FANhyb_icon00000871_a.1.g00001.1FAR1 family protein
FANhyb_icon00000995_a.1.g00001.1FAR1 family protein
FANhyb_icon00001118_a.1.g00001.1FAR1 family protein
FANhyb_icon00003557_a.1.g00001.1FAR1 family protein
FANhyb_icon00005132_a.1.g00001.1FAR1 family protein
FANhyb_icon00006132_a.1.g00001.1FAR1 family protein
FANhyb_icon00006584_a.1.g00001.1FAR1 family protein
FANhyb_icon00011879_a.1.g00001.1FAR1 family protein
FANhyb_icon00013591_a.1.g00001.1FAR1 family protein
FANhyb_icon00018951_a.1.g00001.1FAR1 family protein
FANhyb_icon00019801_a.1.g00001.1FAR1 family protein
FANhyb_icon00030860_a.1.g00001.1FAR1 family protein
FANhyb_icon00030957_a.1.g00001.1FAR1 family protein
FANhyb_icon00031140_a.1.g00001.1FAR1 family protein
FANhyb_icon20472681_s.1.g00001.1FAR1 family protein
FANhyb_icon20621202_s.1.g00001.1FAR1 family protein
FANhyb_rscf00000005.1.g00048.1FAR1 family protein
FANhyb_rscf00000008.1.g00001.1FAR1 family protein
FANhyb_rscf00000068.1.g00012.1FAR1 family protein
FANhyb_rscf00000073.1.g00003.1FAR1 family protein
FANhyb_rscf00000080.1.g00019.1FAR1 family protein
FANhyb_rscf00000111.1.g00008.1FAR1 family protein
FANhyb_rscf00000112.1.g00019.1FAR1 family protein
FANhyb_rscf00000117.1.g00005.1FAR1 family protein
FANhyb_rscf00000117.1.g00006.1FAR1 family protein
FANhyb_rscf00000124.1.g00003.1FAR1 family protein
FANhyb_rscf00000133.1.g00009.1FAR1 family protein
FANhyb_rscf00000134.1.g00005.1FAR1 family protein
FANhyb_rscf00000179.1.g00008.1FAR1 family protein
FANhyb_rscf00000182.1.g00014.1FAR1 family protein
FANhyb_rscf00000242.1.g00010.1FAR1 family protein
FANhyb_rscf00000274.1.g00011.1FAR1 family protein
FANhyb_rscf00000347.1.g00002.1FAR1 family protein
FANhyb_rscf00000425.1.g00002.1FAR1 family protein
FANhyb_rscf00000429.1.g00003.1FAR1 family protein
FANhyb_rscf00000434.1.g00002.1FAR1 family protein
FANhyb_rscf00000434.1.g00005.1FAR1 family protein
FANhyb_rscf00000434.1.g00006.1FAR1 family protein
FANhyb_rscf00000504.1.g00003.1FAR1 family protein
FANhyb_rscf00000584.1.g00002.1FAR1 family protein
FANhyb_rscf00000584.1.g00003.1FAR1 family protein
FANhyb_rscf00000584.1.g00004.1FAR1 family protein
FANhyb_rscf00000745.1.g00008.1FAR1 family protein
FANhyb_rscf00000783.1.g00001.1FAR1 family protein
FANhyb_rscf00000831.1.g00009.1FAR1 family protein
FANhyb_rscf00000839.1.g00001.1FAR1 family protein
FANhyb_rscf00000875.1.g00004.1FAR1 family protein
FANhyb_rscf00000909.1.g00009.1FAR1 family protein
FANhyb_rscf00000955.1.g00001.1FAR1 family protein
FANhyb_rscf00000987.1.g00003.1FAR1 family protein
FANhyb_rscf00001044.1.g00001.1FAR1 family protein
FANhyb_rscf00001221.1.g00003.1FAR1 family protein
FANhyb_rscf00001221.1.g00004.1FAR1 family protein
FANhyb_rscf00001377.1.g00001.1FAR1 family protein
FANhyb_rscf00001694.1.g00002.1FAR1 family protein
FANhyb_rscf00002451.1.g00001.1FAR1 family protein
FANhyb_rscf00002830.1.g00001.1FAR1 family protein
FANhyb_rscf00003813.1.g00001.1FAR1 family protein
FANhyb_rscf00005498.1.g00001.1FAR1 family protein
FANhyb_rscf00005843.1.g00001.1FAR1 family protein
FANhyb_rscf00006742.1.g00001.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885